Penicillin VK is the potassium salt of penicillin V (known as phenoxymethylpenicillin). It is indicated for the treatment of the following infections:
Take preferably on an empty stomach 1 hour before or 2 hours after meals. Penicillin VK may be taken with meals, however food generally delays its absorption.
Usual dosage range of penicillin VK:
High urinary concentrations of penicillin may produce false positive or elevated test results with copper sulfate tests (Benedict’s, Clinitest or Fehling’s).
The most common side effects:
Mechanism of Action
Penicillin V potassium is bactericidal against penicillin-susceptible microorganisms during the stage of active multiplication. It produces its effect by inhibiting biosynthesis of cell-wall mucopeptide. It is not active against the penicillinase-producing bacteria, which include many strains of staphylococci.
Penicillin V potassium has the distinct advantage over penicillin G (benzylpenicillin) in being resistant to inactivation by gastric acid. It may be given with meals; however, blood levels are slightly higher when the drug is given on an empty stomach.
Last Updated: September, 2013