Methocarbamol, a guaifenesin derivative, is a centrally acting muscle relaxant (spasmolytic). It is used as adjunct to rest and physical therapy for the relief of discomfort associated with acute, painful musculoskeletal conditions (e.g. low back pain, neck pain, trauma, strain). Methocarbamol is also used to alleviate symptoms of tetanus.
Is Methocarbamol addictive?
Methocarbamol, at doses greatly above those used therapeutically, has some potential for abuse by persons with histories of drug abuse. However, this potential for abuse or addiction is probably decreased by the accompanying side effects at high doses .
Is Methocarbamol stronger than Carisoprodol (Soma)?
They are completely different medications, though do the same job.
Carisoprodol is considered to be the stronger of the two medications. However, with more strength come more side effects. Carisoprodol is a controlled substance -- it is more dangerous and addictive than other muscle relaxers.
The only head to head comparison of carisoprodol vs methocarbamol was in patients with chronic leg pain . Carisoprodol was superior to methocarbamol for the relief of chronic moderate- to-severe pain.
The recommended starting methocarbamol dosage is 1500 mg (two 750 mg tablets) 4 times daily for 2–3 days. Then, the dose should be reduced to 750 mg 4-6 times daily.
Mechanism of Action
The mode of action of methocarbamol may be related to its sedative properties. It has no direct relaxant effects on tense skeletal muscles, nerve fibers, or the motor endplate.
Methocarbamol is less sedating than tizanidine (Zanaflex) and cyclobenzaprine (Flexeril).
Last Updated: March 02, 2013