Best antidepressant for weight loss
Which antidepressant makes you lose weight? Bupropion (Wellbutrin) is the only one that clearly causes weight loss. In fact, its structure closely resembles that of diethylpropion, a proven appetite suppressant.
Antidepressants that do not cause weight gain are: venlafaxine (Effexor), duloxetine (Cymbalta), trazodone, and nefazodone (Serzone).
Antidepressants most likely to cause weight gain include :
Best antidepressant for anxiety
Escitalopram is effective and well-tolerated first-line option for panic disorder, generalized anxiety, social anxiety and OCD . Also, escitalopram has a role in the treatment of resistant social anxiety.
Recent UK study showed that fluoxetine (in terms of response and remission) and sertraline (in terms of tolerability) are the optimal antidepressants for generalised anxiety disorder .
Best antidepressant for fatigue and low energy
Second only to depressed mood itself, tiredness, fatigue, low energy and motivation - are the most common symptoms of depression. Medications that increase norepinephrine and dopamine may restore energy more rapidly than others.
Bupropion, venlafaxine, fluoxetine and sertraline are the most activating antidepressants and may boost energy, motivation and eliminate fatigue.
Tianeptine (Stablon) is a neuroprotective antidepressant (selective serotonin reuptake enhancer) which elevates mood, enhances attention and memory . Tianeptine is more stimulating than SSRIs and causes neither anxiety nor sedation. Unfortunately, it's not approved in the United States.
Antidepressant with fewest side effects
Escitalopram turns out to be the one with the fewest side effects. Sertraline, bupropion, and citalopram are also among better tolerated.
Last Updated: September 2013