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Flexeril instructions


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Generic Name: Cyclobenzaprine

Brand Name: Flexeril

The following product information is not intended to replace the physician's or manufacturer's instructions.

Flexeril common medical uses:
Flexeril is a skeletal muscle relaxant. This medicine is used with rest, physical therapy, and other measures to relax muscles and relieve pain and discomfort caused by strains, sprains, and other muscle injuries. It relieves muscle spasms of local origin but is not effective in spasms which originate from diseases in the brain or spinal cord. Flexeril works on nerves in the spinal cord to dull nerve impulses or signals to the muscles. Dulling these nerve impulses will help relieve muscle spasms.

How to use Flexeril:
Flexeril comes as a 10 mg tablet to take by mouth. It usually is taken two to four times a day (or 20-40 mg each day in divided doses). Do not exceed 60 mg daily. Do not take this drug for more than 3 weeks without talking to your doctor. Do not take more or less medication than prescribed and follow your doctor's instructions carefully.

Flexeril possible side effects:
Side effects are usually mild and consist of drowsiness, dryness of the mouth, and dizziness. If any of these side effects persist or worsen, contact your doctor.
If you experience any of the following unlikely but serious symptoms, call your doctor immediately:

  • severe skin rash
  • swelling of the face or tongue
  • difficulty breathing or swallowing
  • irregular heart rate
  • chest pain
  • fever
  • seizures.

If you stop taking this medication suddenly, you may experience some withdrawal effects.

Flexeril precaution:
Before taking Flexeril, tell your doctor and pharmacist if you are allergic to Flexeril or any other drugs. Tell your doctor if you have an overactive thyroid gland, heart disease, glaucoma, or difficulty urinating. Inform your doctor if you are pregnant or breast-feeding before taking Flexeril. Flexeril may cause dizziness or drowsiness, so use caution when driving, operating machinery, or performing other hazardous activities. If you experience dizziness or drowsiness, avoid these activities. Remember that alcohol may increase drowsiness and dizziness while you are taking Flexeril.

Flexeril - CONTRA-INDICATIONS:
Serious, potentially fatal reactions may occur if you take Flexeril with an antidepressant drug known as an MAO inhibitor (such as Nardil, Parnate) or if it has been less than 2 weeks since you last took an MAO inhibitor. You should closely follow your doctor's advice regarding discontinuation of MAO inhibitors before taking Flexeril.

Drug interactions:
The best way to avoid harmful interactions is to tell your doctor and pharmacist what prescription and nonprescription drugs you are taking or have taken within the last 2 weeks. Flexeril may interact with antidepressants of both the monoamine oxidase inhibitor class (MAOI9s) and tricyclic antidepressants such as amitriptyline and imipramine. If taken with those drugs, a sudden increase in fever with convulsions may occur.
Many drugs can increase drowsiness associated with cyclobenzaprine:

  • antihistamines (brompheniramine (Dimetane, Bromfed, others)
  • chlorpheniramine (Chlor-Trimeton, Teldrin, others)
  • azatadine (Optimine), clemastine (Tavist), and others)
  • narcotics (pain killers) (meperidine (Demerol), morphine (MS Contin, MSIR, others), propoxyphene (Darvon, Darvocet), hydrocodone (Lorcet, Vicodin), oxycodone (Percocet, Percodan), fentanyl (Duragesic), and codeine (Fiorinal, Fioricet, Tylenol #3))
  • sedatives (phenobarbital (Solfoton, Luminal), amobarbital (Amytal), and secobarbital (Seconal))
  • phenothiazines (chlorpromazine (Thorazine), fluphenazine (Prolixin), mesoridazine (Serentil), perphenazine (Trilafon), prochlorperazine (Compazine), thioridazine (Mellaril), and trifluoperazine (Stelazine))
  • antidepressants (doxepin (Sinequan), nortriptyline (Pamelor), fluoxetine (Prozac), paroxetine (Paxil), sertraline (Zoloft), phenelzine (Nardil), and tranylcypromine (Parnate))
  • high blood pressure drugs.

Overdose:
If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of a Flexeril overdose may include unusual dizziness, drowsiness, low blood pressure (weakness, fainting, confusion), nausea, vomiting, fast or irregular heartbeat.

Missed Dose:
Take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take only your next regularly scheduled dose. Do not take a double dose to make up for the missed one.

Storage:
Store this medication at room temperature and away from excess heat and moisture (not in the bathroom). Keep this and all medications out of the reach of children.

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